personalized medicine deep impact on the healthcare landscape conference document november 28 2006 presented at a world of opportunities hosted by harvard medical school partners center for genetics and genomics 1 definition management patient s disease or disposition using molecular knowledge dna modification proteomics metabolomics to achieve best possible outcome that individual includes improved prevention diagnosis treatment monitoring across both research & clinical care 2 is focused infectious cancer but it widespread source pubmed mckinsey analysis 541 492 369 364 596 606 715 809 122 195 neurological immunological cardiovascular metabolic disorders gi tract respiratory endocrine pharmacogenomics publications top 10 tas number in date hem lymphatic focus are driven tractability science perceived benefits 3 198 263 804 802 359 401 337 276 400 venture capital funding has flowed into peaking 2001 time maximum investment mapping human genome mapped year 100 1990 1998