pain pipeline analysis a treatment area poised to expand 04pl06 november 2004 lucy j sannes ph d published by decision resources inc table of contents executive summary 1 which companies are the major players in management market emerging what is commercial outlook for chapter overview 3 pathophysiology 4 classification 5 based on duration acute vs chronic 7 scope report 8 2 features therapies 9 classes drugs nonopioid analgesics opioid 12 triptans 14 antiepileptic 15 antidepressants local anesthetics 16 targets 17 cannabinoid receptors ion channels 18 calcium channel blockers additional conditions diseases associated with cancer 19 rheumatoid arthritis and osteoarthritis migraine 21 postoperative trauma 23 low back diabetic neuropathy 24 postherpetic neuralgia 25 aids related hiv 26