table of contents 1 introduction 3 2 assessment safety aspirin and other nonsteroidal anti inflammatory drugs nsaids 5 exposure data 6 mechanism action prior fda findings adverse events 4 review gastrointestinal at recommended doses 7 effects in overdose 10 11 nsaid american association poison control centers aapcc reports exposures comparative analysis otc available analgesics 12 excess mortality from bleeding associated with the united states 13 acetaminophen hepatotoxicity 14 comparison 15 conclusions 17 consumer medication use 18 19 recent sources information about actual attitudes medications 20 patterns