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There are millions of surgical procedures performed annually worldwide and the market for wound care products and techniques is significant. In the United States alone, there are over 100,000 surgeries performed daily. Surgical and trauma wounds are, by far, the most common types of wounds addressed in the wound care area. Enjoying market success depends on several factors. Manufacturers must develop a formidable strategy, which involves matching internal capabilities with external opportunities. By choosing to implement such strategies, providers are able to achieve high levels of clinical success while controlling use and costs. Manufacturers are continuing to create well-rounded and advanced products to provide a wider variety of choices. The aging of the population and continued advances in biotechnology drive the wound care industry. The aging world population created increased demand for all types of surgical intervention, particularly cardiovascular, orthopedic, urological and dermatological procedures. The emerging generation of wound care products and technologies are well-positioned to capitalize on this growth. Besides the always-improving synthetic dressing materials, newer technologies in wound treatment include the xenogeneic tissue scaffold, bilayered human dermal substitutes, recombinant growth factors, endoscopic subfascial ligation of venous perforators, and endovascular arterial repair techniques. New wound care products and devices are entering the market with lightening speed, all striving for the best clinical outcomes.

Wound Care, 3rd. Edition, Vol. III: Surgical and Trauma Wounds details total manufacturers’ revenues from the following product categories:

• Wound Closure


• Sutures


• Staples


• Tissue adhesives, sealants and glues


• Anti-infectives


• Surgical and trauma wound management


• Wound cleaners


• Debridement


• Tapes


• Dry dressings


• Moist Dressings


• Alginates


• Films


• Foams


• Hydrocolloids


• Hydrogels


• Biological Dressings


• Artificial Skin


• Collagen


• Growth Factors


• Miscellaneous Treatments

The information and analysis presented in this report are based on an extensive survey of senior management in the prescription women’s health drug industry. Background information was obtained from a comprehensive search of published literature and reports obtained from various government, business, medical trade, and international journals. Key information from published literature was used to conduct interviews with industry executives and product managers to validate and obtain expert opinion on current and future trends in the women’s health industry.

Interviews were also used to confirm and/or adjust market size and market share estimates, as well as in formulating market projections. All market data pertains to the U.S. market at the manufacturers’ level. Revenues in the report are based on sales at the manufacturers’ level for the following markets:

• Wound Closure


• Anti-infectives


• Surgical and Trauma Wound Management


• Moist Dressings


• Biological Dressings


• Miscellaneous Surgical Wound and Trauma Treatments

The market is varied in terms of both product offerings and product maturity. Several of the segments are mature such as anti-infectives, wound management, and sutures and staples of the wound closure market, while others such as biological dressings, some moist dressings, and sealants, adhesives, and glues of the wound closure segment are in the infant stages of development.

Thus some segments within the market are slowing in growth rates while others are driving growth. As identified in the report, conventional, mature products continue to generate the majority of sales; however, their growth rate is slow and limited by the maturity of the product and the competition. Advancements in technology are expected to drive growth during the forecast period.

Product Managers, Marketing Directors in the wound care industry as well as financial and consulting executives are among those that will find this a useful resource.

CHAPTER ONE: EXECUTIVE SUMMARY
Introduction
Scope and Methodology
Size and Growth of the Market
Trends Affecting the Market
Competitive Outlook

CHAPTER TWO: INTRODUCTION AND OVERVIEW
Surgical Wounds
Trauma Wounds
Normal Integument
Epidermis
Dermis
Subcutaneous Tissue
Functions of Skin
Effects of Aging on the Integumentary System
Types of Wound Healing
Defense Against Injury
Mononuclear Phagocyte System
Inflammatory Response
Wound Healing Process
Primary Intention
Secondary Intention
Tertiary Intention
Delays of Wound Healing
Complications of Wound Healing
Hypertrophic Scars and Keloid Formation
Contracture
Dehiscence
Excess Granulation Tissue
Adhesions

CHAPTER THREE: SURGICAL DRESSINGS

CHAPTER FOUR: TREATMENTS
Overview
Wound Closure
Overview and Products
Sutures
Absorbable
Surgical Gut
Synthetic Absorbable Polymers
Nonabsorbable
Surgical Silk
Surgical Cotton
Linen
Surgical Stainless Steel
Synthetic Nonabsorbable Polymers
Staplers and Staples
Tissue Adhesives, Sealants and Glues
Fibrin-based
Collagen-based
Vascular Closing Devices
Polymeric Sealants
Synthetic Adhesives/Glues
Market Segment Conclusion
Anti-Infectives
Overview and Products
Market Segment Conclusion
Surgical and Trauma Wound Management
Overview and Products
Cleansing
Debridement
Tapes
Dry Dressings
Market Segment Conclusion
Moist Dressings
Overview and Products
Alginates
Hydrocolloids
Hydrogels
Films
Foams
Market Segment Conclusion
Biological Dressings
Overview and Products
Artificial Skin
Collagen
Growth Factors
Market Segment Conclusion
Miscellaneous Surgical Wound and Trauma Treatments
Overview and Products
Market Segment Conclusion

CHAPTER FIVE: MARKET SIZE AND FORECAST SUMMARY

CHAPTER SIX: COMPETITIVE ANALYSIS
Total Surgical and Trauma Wound Market
Competitive Market Share by Segment
Wound Closure
Anti-Infectives
Surgical and Trauma Wound Management
Moist Dressings
Biological Dressings
Miscellaneous Treatments

CHAPTER SEVEN: INDUSTRY DEVELOPMENTS
Product Categorization
New Products
Reimbursement
Novel Treatments
Miscellaneous Treatments
Honey Treatment
Battle-ready Bandage Treatment
Silverlon
Low Intensity Laser Therapy
In Development
Merrem IV
OrCel
Allox
Thymosin Beta 4
Encelle E Matrix
KGF-2
BioFoam
CoFoam Polyurethne Composite
LyphoDerm
KGF-2
Demegen
HB50
Other Miscellaneous Developments
Psychosocial Factors in Wound Healing
Scar Treatment
Keloid Scars
Hypertrophic Scars
Hormones and Wound Healing
Surgical Infection
Demographics and Epidemiology

CHAPTER EIGHT: COMPANY PROFILES
Abbott Vascular Devices
Baxter BioScience
Bertek Pharmaceuticals, Inc.
Carrington Laboratories, Inc.
ConvaTec, Ltd.
Datascope Corporation
Ethicon, Inc.
GlaxoSmithKline Plc
Healthpoint, Ltd.
Johnson & Johnson
Kinetic Concepts, Inc.
Pfizer, Inc.
Smith & Nephew, plc
St. Jude Medical, Inc.
United States Surgical

APPENDIX: COMPANY DIRECTORY

LIST OF EXHIBITS
CHAPTER ONE: EXECUTIVE SUMMARY
Figure 1-1: Worldwide Surgical and Trauma Wound
Product Revenues by Segment 1999-2009 5 CHAPTER FOUR: TREATMENTS
Table 4-1: Selected Absorbable Sutures by Manufacturers and Products 32
Table 4-2: Selected Nonabsorbable Sutures by Manufacturers and Products 36
Table 4-3: Selected Staplers and Staples Manufacturers and Products 40
Table 4-4: Selected Tissue Adhesives, Sealants, and Glues Manufacturers and Products 46
Table 4-5: World Market for Wound Closure Products by Type (Sutures; Staplers and Staples; Tissue Adhesives, Sealants, and Glues) 1999-2009 47
Table 4-7: Selected Topical Brand Name Anti-Infectives 49
Table 4-8: The World Market for Anti-Infectives for Surgical and Trauma Wounds 1999-2009 50
Table 4-9: Toxicity Index for Selected Wound Cleansers 52
Table 4-10: Selected Cleansing Agents Currently on the Market 53
Table 4-11: Selected Debridement Agents Currently Available 55
Table 4-12: Selected Adhesive Strips and Tapes Currently on the Market 58
Table 4-13: Selected Dry Dressing (Woven and Nonwoven) Currently on the Market 60
Table 4-14: World Market for Wound Management Products for Surgical and Trauma Wounds Revenues by Segment (Cleansing, Debridement, Tapes, Dry Dressings) 1999-2009 61
Table 4-15: Selected Alginate Products Currently on the Market 63
Table 4-16: Selected Hydrocolloid Products Currently on the Market 68
Table 4-17: Selected Hydrogel Products Currently on the Market 71
Table 4-18: Selected Films Currently on the Market 76
Table 4-19: Selected Foam Products Currently on the Market 79
Table 4-20: Moist Dressings for Surgical and Trauma Wounds, Revenues by Segment (Alginates, Hydrocolloids, Hydrogels, Films,Foams) 1999-2009 83
Table 4-21: Selected Artificial Skin Products Currently on the Market 87
Table 4-22: Selected Collagen Products Currently on the Market
Table 4-23: World Market for Biological Dressings for Surgical and Trauma Wounds, Revenues by Segment (Artificial Skins, Collagen Products, Other Products) 1999-2009 93
Table 4-24: Selected Miscellaneous Surgical Wound and Trauma Treatment Manufacturers and Products 98
Table 4-25: World Market for Miscellaneous Surgical and Trauma Wound Treatments 1999-2009: 99

CHAPTER FIVE: MARKET SIZE AND FORECAST SUMMARY
Table 5-1: World Surgical and Trauma Wound Product Revenues by Segment 1999-2009 102
Figure 5-1: Surgical and Trauma Wound Care Revenues by Segment 1999-2009 103
Table 5-2: Surgical and Trauma Wound Care Share by Segment 1999-2009 104
Figure 5-2: Surgical and Trauma Wound Care Market Share by Segment 2004 vs 2009 105

CHAPTER SIX: COMPETITIVE ANALYSIS
Table 6-1: Major Competitors and Segments of Participation 2004 109-112
Table 6-2: The World Surgical and Trauma Wound Care Market Revenues and Market Share by Leading Supplier 2004 113
Figure 6-1: Surgical and Trauma Wound Care Market Share by Leading Supplier 2004 114
Table 6-3: Surgical and Trauma Wound Closure Revenues and Market Share by Leading Supplier 2004 115
Table 6-4: Anti-Infectives for Surgical and Trauma Wounds Revenues and Market Share by Leading Supplier 2004 116
Table 6-5: Surgical and Trauma Wound Management Revenues and Market Share by Leading Supplier 2004 117
Table 6-6: Moist Dressings for Surgical and Trauma Wounds Revenues and Market Share by Leading Supplier 2004 118
Table 6-7: Biological Dressings for Surgical and Trauma Wounds Revenues and Market Share by Leading Supplier 2004 119
Table 6-8: Miscellaneous Surgical and Trauma Wound Treatments Revenues and Market Share by Leading Supplier 2004 120

CHAPTER SEVEN: INDUSTRY DEVELOPMENTS
Table 7-1: Global and U.S. Population by Age Group and Sex 1999, 2004, and 2009 145
Figure 7-1: U.S. Population by Age Group, 1999, 2004, and 2009 146
Figure 7-2: Global Population by Age Group, 1999, 2004, and 2009 146
Table 7-2: Global and U.S. Yearly Incidence of Surgical and Trauma Wounds by Type 147