Ajouter aux favoris   Ajouter cette page à mon bookmark --- SOCIAL BOOKMARKING --- Digg Furl del.icio.us Netscape

Orthopedic biomaterial products, which can be organic or synthetic in nature, are implanted into or near a bone fracture to facilitate healing or to compensate for a lack or loss of bone tissue. Biomaterials used in orthopedic surgery include autografts, allografts, xenografts, ceramics, polymers, bone growth factors and synovial fluid substitutes. Among the prominent applications for orthopedic biomaterials are surface coatings for hip prostheses, bone cements, bone defect fillers, and fracture fixation plates.

Technological advancement and an aging, active population are the principal drivers behind the market for orthopedic biomaterials.
Kalorama's Orthopedic Biomaterials, World Market, one of the few resources available on this market, looks at the Market for biomaterials, including the following segments:

• Allograft Products (including DBM, Machined Bone and Standard Allograft)


• Ceramic Products


• Polymer Products


• rhBMP Products


• HA Viscosupplemental Products

As part of Kalorama Information's exhaustive coverage of the orthopedic biomaterials market for each area, the following data are provided:

• Historical Revenues from 2001-2005


• Forecasts to 2012


• Competitive Market Share


• Discussion of Issues and Trends


• Review of New Products


• Company Profiles

A truly global resource, this report provides information on the following world regions:

• US


• Europe


• Asia


• Rest of World

The information for this report was gathered using both primary and secondary research including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary method of gathering information.

For the purpose of this study, Kalorama Information conducted interviews with key industry officials, consultants, health care providers, orthopedic surgeons, research institutes, and government personnel. These sources were the primary basis for information specifically relating to trends in the orthopedic biomaterials industry, revenue and market share data presented in this report. Specific interviews with orthopedic implant device and biomaterial company representatives included marketing directors, division managers, and product representatives.

CHAPTER ONE: EXECUTIVE SUMMARY
* Overview
* Scope and Methodology
* Musculoskeletal Conditions/Treatments
* Prevelance of Musculoskeletal Conditions
* Most Common Musculoskeletal Conditions
* Joint Replacement Procedures
* Future Directions in the Treatment of Musculoskeletal Conditions
* Gene Therapy
* Stem Cell Therapy
* Orthopedic Biomaterials Products and Markets
* World Orthopedic Biomaterials Market
* Market Segment Analysis
* Allograft Bone Substitutes
* Ceramic Bone Substitutes
* Polymer Bone Substitutes
* rhBMP
* HA Viscosupplemental Substitutes

CHAPTER TWO: INTRODUCTION Overview of the Form/Function of Bone
Bone Characteristics
Types of Bone
Cortical Bone
Cancellous Bone
Bone Cells
Osteoblasts
Osteoclasts
Osteocytes
The Functions of Bone
Bone Matrix
Joint Components
Cartilage
Joint Capsule
Synovium
Ligaments
Prevalence of Musculoskeletal Conditions
Musculoskeletal Conditions In Europe
Musculoskeletal Conditions In the United States
Common Musculoskeletal Conditions
Osteoarthritis
Osteoporosis
Bone Fractures
Ligament Injuries
Joint Replacement Procedures
Introduction
Most Common Procedures
Knee Reconstruction
Hip Reconstruction
Spinal Fusion
Future Directions in the treatment of Musculoskeletal conditions
Gene Therapy
Stem Cell Therapy

CHAPTER THREE: ORTHOPEDIC BIOMATERIALS
* Overview
* Brief History of Orthopedic Biomaterials
* Categories of Orthopedic Biomaterials
* Bone Grafts
* Types of Bone Grafts
* Autografts
* Advantages
* Disadvantages
* Allograft
* Disadvantages
* Xenografts
* Disadvantages
* Allograft Bone Graft Substitutes
* Overview
* Demineralized Bone Matrix
* Types of DBM Products
* Conventional Allograft
* Machined Allograft
* Ceramic-based Bone Graft Substitutes
* Overview
* Types of Materials
* Hydroxyapatites
* Ceramic Coated Joint Implants
* Coralline Hydroxyapatite
* Tricalcium Phosphate
* Calcium Phosphate
* Calcium Sulphate
* Polymer-based Bone Graft Substitutes
* Overview
* Nondegradable Polymers
* Bioabsorbable Polymer Biomaterials
* Polylactic Acid (PLA)
* Polyglycolic Acid (PGA)
* Copolymers
* Factor-based Bone Graft Substitutes
* Overview
* Types of Growth Factors
* Bone Morphogenic Protein (BMP)
* Transforming Growth Factor-Beta (TGF-â)
* Fibroblast Growth Factors (FGFs)
* Insulin-Like Growth Factors (IGFs)
* Platelet-Derived Growth Factor (PDGF)
* Carriers/Delivery Systems for Growth Factors
* Type-1 Collagen
* Demineralized Bone Matrix (DBM)
* Polymers
* Ceramics
* Hyaluronic Acid
* Gene Therapy
* Hyaluronic Acid Synovial Fluid Substitute
* Overview
* Viscosupplementation

CHAPTER FOUR: ORTHOPEIC BIOMATERIAL MARKET ANALYSIS
World Market Analysis and Forecast
Orthopedic Biomaterial Market Drivers
Orthopedic Biomaterials Market Forecast
World Regional Markets
Market Segment Analysis
Market Value and Growth by Segment
Allograft Bone Market Analysis
Allograft Applications
Allograft Bone Products
DBM
Machined Bone Products
Allograft Market
Market Drivers and Limitations
Allograft Competitors’ Market Share
Ceramic Bone Substitute Market Analysis
Ceramic Applications and Products
Ceramic-coated Implants
Ceramic-based Bone Substitute Products
Ceramic Biomaterials Market
Market Drivers and Limitations
Ceramic Competitors’ Market Share
Polymer Bone Substitutes Market Analysis
Nondegradable Polymers
PEEK Applications
Bioabsorbable Polymers
Applications for Polymer Bioabsorbable Biomaterials
Bioaborable Polymers as Delivery Systems
Combination Products
Polymer Biomaterials Market
Market Drivers
Competitors’ Market Share
Bone Morphogenetic Proteins Market Analysis
Products and Applications
InFuse and InductOS (RhBMP-2)
OP-1 (rhBMP-7)
Carrier Materials for BMPs
BMP World Market
Market Drivers
HA Viscosupplementational Market Analysis
HA Viscosupplemental Products and Applications
HA Viscosupplementational Market
Market Drivers
HA Viscosupplemental Competitors’ Market Share

CHAPTER FIVE: COMPANY PROFILES
* Biomet, Inc.
* Genzyme Corporation
* IsoTis OrthoBiologics, Inc.
* LifeCell Corporation
* Medtronic Sofamor Danek, Inc.
* Orthovita, Inc.
* Osteotech, INC.
* Smith & Nephew, Inc.
* Stryker Corporation
* Synthes, Inc
* Tutogen Medical, Inc.
* Wright Medical Group, Inc.

TABLE OF EXHIBITS
Exhibit 1-1: World Orthopedic Biomaterials Market
Exhibit 1-2 World Orthopedic Biomaterials Market (in millions of dollars)
Exhibit 1-3: Segment Market Share, 2006 (Allograft Products, Ceramic Products, Polymer Products, rhBMP Products, HA Viscosupplemental Products)
INTRODUCTION
Exhibit 2-1: Emergency Room Visits for Muscolskeletal Symptoms, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
Exhibit 2-2: Emergency Room Visits for Fractures, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
Exhibit 2-3: Knee Replacement Procedures, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
Exhibit 2-4 Hip Replacement Procedures, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
Exhibit 2-5: Spinal Fusion Procedures, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
ORTHOPEDIC BIOMATERIAL MARKET ANALYSIS
Exhibit 4-1: World Orthopedic Biomaterials Market
Exhibit 4-2: World Regional Biomaterials Markets by Revenue, 2006
Exhibit 4-3 World Regional Biomaterilas Markets by Percentage, 2006
Exhibit 4-4: Orthopedic Biomaterials Market by Segment (Allograft Products, Ceramic Products, Polymer Products, rhBMP Products, HA Viscosupplemental Products)
Exhibit 4-5: Segment Market Share in 2006 (Allograft Products, Ceramic Products, Polymer Products, rhBMP Products, HA Viscosupplemental Products)
Exhibit 4-6: Segment Market Share in 2012 (Allograft Products, Ceramic Products, Polymer Products, rhBMP Products, HA Viscosupplemental Products)
Exhibit 4-7: Sample Allograft Distribution Relationships (Tissue, Source, Processor, Distributor)
Exhibit 4-8: Selected Allograft Prdoucts on the Market v Exhibit 4-9: World Allograft Market
Exhibit 4-10: Allograft Product Categories, by Percent, 2006 (DBM, Machined Bone, Standard Allograft)
Exhibit 4-11: Allograft Market Share, 2006
Exhibit 4-12: Selected Ceramic-Based Biomaterials (Product, Manufacturer, Description)
Exhibit 4-13: World Market for Ceramic-Based Biomaterials
Exhibit 4-14: Ceramic-Based Products Market Share,2006
Exhibit 4-15: Selected Polymer Products (Product, Composition, Company)
Exhibit 4-16: Bioresorbable Polymer Resorption (Polymer, Crystallinity, Beginning of Resorption, Time of Complete Resorption)
Exhibit 4-17: World Polymer Biomaterials Market (millions)
Exhibit 4-18: Polymer Biomaterials Market Share, 2006
Exhibit 4-19: Various Carrier Materials Available for BMPs
Exhibit 4-20: The World Market for rhBMP Products
Exhibit 4-21 Osteoporosis and Low Bone Mass in the United States
Exhibit 4-22 Definitions and Charactertistics of Hyaluronic Acid and Hylans
Exhibit 4-23 Osteoporosis and Low Bone Mass in the United States
Exhibit 4-24: Selected HA Viscosupplemental Products
Exhibit 4-25: World HA Viscosupplementational Market (in millions of dollars)
Exhibit 4-26: World Viscosupplementation Market Share, 2006