Introduction

Alnylam Pharmaceuticals's main focus is to discover and develop novel therapeutics based on RNA interference for the treatment of wide range of diseases such as ocular, central nervous system and respiratory diseases. The company seeks to build a franchise of RNAi therapeutics through its own internal efforts as well as partnering with other pharmaceuticals.

Scope

TABLE OF CONTENTS
Overview 1
Catalyst 1
Summary 1
Company Structure 7
Company Overview and Key Facts 7
Business Description 8
History 10
Locations and Subsidiaries 13
Company Financials 14
Stock Market Performance 14
P&L 16
Balance Sheet 19
Cash Flow 19
Business Segment Performance 20
Products & Services 21
Pipeline Products 21
AC Forecast Product Sales 24
Competitors and Strategic Business Relationships 25
Top Competitors 25
Key Suppliers 26
Key Clients 26
Shareholding Structure 27
Strategy 28
Company View 28
Strategy 30
SWOT Analysis 32
Overview 32
Strengths 33
Weaknesses 35
Opportunities 36
Threats 37
Value Chain Analysis 39
Overview 39
Discovery and Product Development 40
Scorecard 41
Overview 41
Scorecard Analysis 42
Key Employees 43
List of Key Employees 43
Key Employee Biographies 44
Financial and Operational Overview 51
Financial and Operational Overview 51
Appendix 53
Ask the analyst 53
Datamonitor consulting 53
Disclaimer 53


TABLE OF FIGURES
Figure 1: Alnylam - Operating Revenue/Cost Analysis, 2002-2006 ($ Mn) 17


TABLE OF TABLES
Table 1: Alnylam - Key Facts 7
Table 2: Alnylam - Other Locations and Subsidiaries 13
Table 3: Alnylam - Year-End Share Price and Market Capitalization, 2002-2006 ($) 14
Table 4: Alnylam - Key Events Impacting Share Price Performance 15
Table 5: Alnylam - Operating Revenue/Cost Analysis, 2002-2006 ($ Mn) 16
Table 6: Alnylam - Operating Cost Ratio Analysis, 2002-2006 (% of total revenues) 17
Table 7: Alnylam - Balance Sheet, 2002-2006 ($ Mn) 19
Table 8: Alnylam - Cash Flow, 2002-2006 ($ Mn) 19
Table 9: Alnylam - Revenue Breakdown, 2002-2006 ($ Mn) 20
Table 10: Alnylam – In-house Pipeline Products 21
Table 11: Alnylam – Collaboration Pipeline Products 22
Table 12: Alnylam – Forecast Sales, 2006-2010 ($ Mn) 24
Table 13: Alnylam – Top Competitors 25
Table 14: Alnylam – Key Suppliers 26
Table 15: Alnylam – Key Clients 26
Table 16: Alnylam - Key Shareholders 27
Table 17: Alnylam - SWOT Analysis Summary 32
Table 18: Alnylam – Value Chain Analysis 39
Table 19: Alnylam - Scorecard 41
Table 20: Alnylam - Key Employees 43
Table 21: Alnylam - Financial and Operational Overview 51