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The commercial production of threonine, one of the amino acids, started from the 1990s. About 19 kinds of amino acids are being produced in China now, and the production scale of the manufacturers is very small. The Chinese manufacturers mainly focus on pharma-grade threonine.

China is a market with great potential for amino acid. According to the statistics in mid 2001, there were over 100 amino acids factories in China. The actual production is estimated to be more than 500,000t/a in China, but about 90% ~ 95% is glutamic acid. There is a lot space for other amino acids. The central government has already implemented many policies to guide the direction of amino acids.

China is a promising market for threonine. But at present China's market demand for threonine is only about 100t/a.

The small market volume is mainly because Chinese producers only aim at the market of amino acid transfusion. In China, the amino acid transfusion industry developed fast in the previous years. In 1989, there were only 8 manufacturers producing amino acid transfusion, but the number of manufacturers climbed up to 80 in 1999.

The feed grade threonine relies on import. Now promoted by the rapid growth of livestock industry and pharmaceuticals, the production of threonine will be more flourishing, and China's import of threonine is likely to decrease in the future.

In this report, comprehensive tel interview with experts within the industry and further analysis in detail are carried out to verify the up-to-date situation of the market.



Wuxi Jinghai Amino Acid Co., Ltd., Zhejiang Guoguang Biochemical Stock Co., Ltd., Chengdu Kaitai Company, Tianjin Tian’an Stock Co., Ltd, Shanghai Ajinomoto Co., Ltd.

TABLE OF CONTENTS
Executive Summary
Methodology
I Overall Situation of Amino Acids and Threonine
I-1 Brief Introduction to Amino Acids Situation in China – Pharmaceutical Grade Materials in Particular
I-1.1 Brief History & Current Situation of Amino Acid Production in China
I-1.2 Production Methods & Research Field of Amino Acids in China
I-1.3 Brief Introduction to Some Specific Amino Acids
I-1.3.01 Alanine
I-1.3.02 Arginine
I-1.3.03 Aspartic Acid
I-1.3.04 Cysteine
I-1.3.05 Cystine
I-1.3.06 Glutamic Acid
I-1.3.07 Glycine
I-1.3.08 Histidine
I-1.3.09 Isoleucine
I-1.3.10 Leucine
I-1.3.11 Lysine
I-1.3.12 Methionine
I-1.3.13 Phenylalanine
I-1.3.14 Proline
I-1.3.15 Serine
I-1.3.16 Threonine
I-1.3.17 Tryptophan
I-1.3.18 Tyrosine
I-2 Brief History of Threonine Development in China
I-3 Research Achievement & Major Researchers of Threonine in China
II Situation of Feed Grade Threonine in China
II-1 Current Production Situaton of Feed Grade Threonine in China
II-2 Analysis on the Import of Feed Grade Threonine in 2002 and First Half 2003
II-3 Estimation on the Deamnd for Feed Grade Threonine in China
II-3.1 Introduction
II-3.2 Estimation on demand for feed grade threonine in 2002
III Situation of Pharmaceutical Grade Threonine in China
III-1 Current Production Situation of Pharmaceutical Grade Threonine in China
III-2 Analysis on the Export of Pharmaceutical Grade Threonine in 2002 and First Half 2003
III-3 Estimation on the Demand for Pharmaceutical Grade Threonine in China
II Appendix: Manufacturers Information
Appendix: Brief Situation of Major Manufacturers of Threonine in China
II-1 Producers of Threonine: Feed Grade, Food Grade & Pharma Grade
II-1.01 Wuxi Jinghai Amino Acid Co., Ltd. (Feed + Pharma)
……….
II-1.07 Shantou Hongwei Amino Acid Factory (Pharma)
II-2 Potential Producers of Threonine
II-2.01 Tianjin Tian’an Stock Co., Ltd
……….
II-2.03 Nanning Only-Time Rexim Pharmaceutical Co., Ltd.
II-3 Pocessors of Food Grade Threonine & Pharma Grade Threonine
II-3.01 Shanghai Ajinomoto Co., Ltd.
……..
II-3.11 Shanghai Kangda Amino Acid Facrtory
II-4 Manufacturers Who Stopped Processing of Pharma Grade Threonine
II-4.01 Hangzhou Guangchuan Biotechnology Co., Ltd.
………..
II-4.03 Shanghai Guanshengyuan-Kyowa Amino Acid Co., Ltd.
Conclusion
Suggestions & Recommendations

LIST OF TABLES
Table I-1.1-1 Production of pharmaceutical grade amino acid in the past
Table I-1.2-1 Production method & research focus of amino acids in China
Table I-1.3.01-1 Price trend of L-alanine in the past (on CNF NY base, unit: USD/kg)
Table I-1.3.03-1 Price trend of L-aspartic acid in the past (on CNF base, unit: USD/kg)
Table I-1.3.04-1 Price trend of L-cysteine in the past: (on CNF base of cysteine HCL mono, unit: USD/kg)
Table I-1.3.05-1 Price trend of L-cystine in the past (on CNF base, unit: USD/kg)
Table I-1.3.09-1 Price trend of L-isoleucine in the past: (on CNF base, unit: USD/kg)
Table I-1.3.10-1 Price trend of L-leucine in the past: (on CNF base, unit: USD/kg)
Table I-1.3-11-1 Price trend of pharmaceutical grade L-lysine (USD23/AJI88) in the past (on CNF base, unit: USD/kg)
Table I-1.3.13-1 Price trend of DL-phenylalanine in the past (on CNF base, unit: USD/kg)
Table I-1.3.14-1 Price trend of L-proline in the past (on CNF base, unit: USD/kg)
Table I-1.3.16-1 Price trend of L-threonine in the past (on CNF base, unit: USD/kg)
Table I-1.3.18-1 Price trend of L-Tyrosine in the past (on CNF base, unit: USD/kg)
Table I-1.3.19-1 Price trend of L-valine in the past (on CNF base, unit: USD/kg)
Table II-2-1 Active importers of feed grade threonine in 2002
Table II-2-2 Origin of feed grade threonine in 2002 and first half 2003 Table II-2-3 Active importers of feed grade threonine in first half 2003
Table II-3.1-1 Theoretical demand for threonine
Table II-3.1-2 Production of feed in 2002
Table II-3.2-1 Estimation on the demand for threonine in 2002
Table III-1-1 List of pharma-grade threonine suppliers in China -1
Table III-1-2 List of pharma-grade threonine suppliers in China -2
Table III-1-3 List of pharma-grade threonine suppliers in China –3
Table III-1-4 Pharma-grade threonine supplier that stopped the production
Table III-2-1 Active exporter of pharmaceutical grade threonine in 2002
Table III-2-2 Export destination of pharmaceutical grade threonine in 2002 and first half 2003
Table III-2-3 Active exporter of pharmaceutical grade threonine in first half 2003
Table III-3-1 The production of amino acid transfusion in China (MTs)
Table III-3-2 Composition of amino acid in China (Unit: by weight, %)
Table III-3-3 Demand for threonine in the past years (MTs)
Table III-3-4 The top 2 makers of each amino acid transfusion in 1998
Table III-3-5 The top 3 makers of each amino acid transfusion in 2002 (unit: 1,000 bottles)
Table III-3-6 Production of amino acid nutrient liquid in the past (nut: million bottles)